What Is DHT? What is its
Role in Hair Loss?
Both men and women tend to lose hair due to some hormonal
changes in the body. It is mainly the alterations in the metabolism of androgen
in the body that brings about hair loss. Androgen is the male hormone that plays
a very important role in both hair loss and hair growth. This metabolism of
androgen gets involved with an enzyme, the 5 alpha reductase which tends to
combine with the male hormone, testosterone to give DHT (Dihydrotestosterone).
This DHT is the natural metabolite of the human body that is the main reason for
dht hair loss
Blocks DHT Picture:
The most important structure of a hair follicle is the dermal papilla, which is
responsible for hair growth. The cell of this dermal papilla divides and
differentiates to form a new hair follicle. As this dermal papilla lies in
direct contact with blood capillaries of the skin, it is responsible for
deriving nutrients for hair follicle growth. This dermal papilla has many
receptors for androgens; where men have more androgenic receptors here than
It is very important for a person to have proper nutrition to maintain hair. So
when DHT reaches the hair follicles and dermal papilla, it tends to prevent
proteins, vitamins and minerals from providing the needed nourishment to sustain
life in the hair of these follicles. With this, the hair follicles tend to
reproduce at a slower rate and this in turn either shortens the growing phase of
the hair follicles or lengthens its resting stage.
DHT is also responsible for shrinking hair follicle with which the hair follicle
gets smaller and finer. This is referred to as miniaturization with which the
hair ultimately falls off. This is how DHT is responsible for about 95% of hair
loss. The men or women who lose more hair are those who are genetically
pre-disposed in producing more DHT than others.
In addition to all this, DHT tends to create a wax like substance around the
hair roots and it is this accumulation of DHT in the hair follicles and roots
that gives rise to male and female pattern hair loss. There is a type of
treatment that blocks the synthesis of DHT at molecular level to cure both male
pattern and female pattern hair loss. This is done by using one of the many
natural DHT blockers and drugs that are used for medical hair restoration.
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